解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::We have previously shown that human peripheral blood lymphocytes that do not adhere to natural killer (NK)-sensitive target cell monolayers are at least partially depleted of NK activity. To demonstrate directly that NK effector cells adhere to the monolayers, we have now recovered the adherent populations by treatmen...
journal_title:Immunobiology
pub_type: 杂志文章
doi:10.1016/S0171-2985(82)80052-1
更新日期:1982-05-01 00:00:00
abstract::Immunocytochemical studies on both the light-microscopic and electron-microscopic levels proved that peritoneal resident macrophages derive from a precursor cell in the bone marrow. Evidence that this precursor cell differs from that of the monocyte is described. Progenitor cells of peritoneal resident macrophages wer...
journal_title:Immunobiology
pub_type: 杂志文章,评审
doi:10.1016/S0171-2985(82)80075-2
更新日期:1982-04-01 00:00:00
abstract::A "lectin-like" receptor for bacterial cell wall sugars, originally described in the membrane of mouse peritoneal macrophages, which facilitates binding of various bacteria to the macrophage surface, has now been shown to be present on most phagocytes from a variety of species. The role of such a receptor in the infla...
journal_title:Immunobiology
pub_type: 杂志文章
doi:10.1016/S0171-2985(82)80090-9
更新日期:1982-04-01 00:00:00
abstract::A case of a 35-year-old female with multiple sclerosis is reported who developed without apparent prior sensitization a lymphocytotoxic antibody with anti-HLA-B8 specificity. The antibody persisted for several years with the same titer. The cytotoxic activity of the patient's serum was contained within the IgM fractio...
journal_title:Immunobiology
pub_type: 杂志文章
doi:10.1016/S0171-2985(82)80002-8
更新日期:1982-02-01 00:00:00
abstract::The phenotype frequency of the platelet-specific antigens P1A1/A2 ( = Zw(a,b)) in the German population (N = 711) is 97.75% and 2.25% respectively. The corresponding gene frequencies are P1A1 0.85; P1A2 0.15. The P1A1 determinant is codominantly inherited (19 families; 151 family members). There is a strong gene dosag...
journal_title:Immunobiology
pub_type: 杂志文章
doi:10.1016/S0171-2985(82)80001-6
更新日期:1982-02-01 00:00:00
abstract::The distribution of membrane-associated nucleotide pyrophosphatase activity has been investigated on mouse leucocytes of different origin. It is shown that enzyme-specific activity is higher on bone-marrow cells than on cells derived from peripheral organs. Since thymus lymphocytes show the lowest activity, it is obvi...
journal_title:Immunobiology
pub_type: 杂志文章
doi:10.1016/S0171-2985(11)80029-X
更新日期:1982-01-01 00:00:00
abstract::Spleen exposure to ultrasound has been reported to influence antibody response to sheep red blood cell injection in mice (decreased hemagglutination and hemolytic titers and IgM, IgG2a and IgG2b levels and elevated IgG1 levels). In a controlled clinical trial, we investigated the possible immunosuppressive side-effect...
journal_title:Immunobiology
pub_type: 临床试验,杂志文章
doi:10.1016/S0171-2985(11)80016-1
更新日期:1982-01-01 00:00:00
abstract::Lymphocytes from spleen, thymus and lymph nodes from individual young adult (3--4 months) and aged (26--30 months) NMRI mice were stimulated with the mitogens Con A, PHA and LPS. 24 hours later, the number of cell with increased RNA-content (G1 cells) was determined by cytofluorometry. In parallel the 3H-thymidine inc...
journal_title:Immunobiology
pub_type: 杂志文章
doi:10.1016/S0171-2985(81)80014-9
更新日期:1981-06-01 00:00:00
abstract::Five mouse hybridoma cell lines producing monoclonal antibody against bovine luteinizing hormone (LH) have been established and the respective antibodies characterized by radioimmunoassay, immunofluorescence and immunoelectrophoresis. All antibodies belong to the IgG class and bind to staphylococcus protein A. Intrasp...
journal_title:Immunobiology
pub_type: 杂志文章
doi:10.1016/S0171-2985(81)80047-2
更新日期:1981-01-01 00:00:00
abstract::LIF activity production by ConA-stimulated mononuclear cells was tested by measuring granulocyte migration from clotted plasma droplets placed in Microtest II plates. 90 min. incubation of MNC cultures with ConA assured a significant LIF activity in the 24 h. culture supernatants. Removal of the adherent cells after C...
journal_title:Immunobiology
pub_type: 杂志文章
doi:10.1016/S0171-2985(81)80097-6
更新日期:1981-01-01 00:00:00
abstract::Human T-lymphocyte clones showing proliferative and cytotoxic responses specific for HLA antigens were isolated. To obtain enriched numbers of functionally active colonies, the cells were first sensitized in vitro in a tertiary mixed lymphocyte culture (MLC), using 10 stimulating cells for each responding cell. To ass...
journal_title:Immunobiology
pub_type: 杂志文章
doi:10.1016/s0171-2985(81)80062-9
更新日期:1981-01-01 00:00:00
abstract::Peritoneal exudate T lymphocytes (PETLs) that mediate delayed-type hypersensitivity (DTH) to sheep red blood cells in mice were modified by in vitro treatment methods which modify surface carbohydrate constituents. Neuraminidase treatment resulted in the release of both N-acetylneuraminic acid and N-glycolyl-neuramini...
journal_title:Immunobiology
pub_type: 杂志文章
doi:10.1016/S0171-2985(81)80046-0
更新日期:1981-01-01 00:00:00
abstract::Suppressor monocytes, Concanavalin A(ConA)-induced suppressor T cells, and short-lived suppressor lymphocytes have been describe in humans. The present study was performed to evaluate spontaneous suppression in a test system similar to that employed for the demonstration of ConA-induced suppressor cells: Lymphocytes w...
journal_title:Immunobiology
pub_type: 杂志文章
doi:10.1016/S0171-2985(81)80087-3
更新日期:1981-01-01 00:00:00
abstract::Polyclonally activated lymphoblasts, transferred to syngeneic recipient mice, elicited a host T-cell-mediated "response" in vivo. These T cells, which "responded" in vivo to syngeneic lymphoblasts (i.e. in vivo primed "responder" T-cell population), acquired the capacity to "stimulate" a "response" of syngeneic T cell...
journal_title:Immunobiology
pub_type: 杂志文章
doi:10.1016/S0171-2985(80)80015-5
更新日期:1980-12-01 00:00:00
abstract::Cytophotometric measurements of DNA, dry mass (total proteins) and surface localized IgM and Ia were performed on individual cells of a Burkitt lymphoma derived cell line after X-irradiation and after polyploidization. Blockage of cell division was achieved with 250 r, and an arrest in G2 was found 48 hr after irradia...
journal_title:Immunobiology
pub_type: 杂志文章
doi:10.1016/S0171-2985(80)80099-4
更新日期:1980-07-01 00:00:00
abstract::Supernatants from Concanavalin A-stimulated murine spleen cells were subjected to hydrophobic interaction chromatography on phenyl-Sepharose. Macrophage cytotoxicity factor (MCF), macrophage migration inhibitory factor (MIF), T-helper cell-replacing factor (TRF) and colony-stimulating factor (CSF) were bound at high i...
journal_title:Immunobiology
pub_type: 杂志文章
doi:10.1016/S0171-2985(80)80098-2
更新日期:1980-07-01 00:00:00
abstract::Ribosomal 30S and 50S subunits as well as total proteins from the large subunit of E. coli ribosomes were found to be potent mitogens for both human adult and cord blood lymphocytes. On the other hand, the RNA fraction of the 50S subunit had only a weak stimulatory capacity suggesting that the protein moiety contains ...
journal_title:Immunobiology
pub_type: 杂志文章
doi:10.1016/S0171-2985(80)80079-9
更新日期:1980-01-01 00:00:00
abstract::Human sera enhanced spontaneous cell-mediated cytotoxicity (SCMC), while anti-IgG (Fab') 2 treatment decreased this cytotoxic activity of human lymphocytes for an in vitro growing cell line (K--562). Trypsin treatment of the effector cells considerably decreased the cytotoxic potential. However, a significant cytotoxi...
journal_title:Immunobiology
pub_type: 杂志文章
doi:
更新日期:1979-09-01 00:00:00
abstract::BASILEA rabbits lack the expression of chi-polypeptide chains and compensate for this lack with expression of lambda polypeptide light chains. These rabbits were immunized with streptococcal group A-variant vaccines. The heterogeneity of the lambda polypeptide chains of specific antibodies was analyzed and compared wi...
journal_title:Immunobiology
pub_type: 杂志文章
doi:
更新日期:1979-08-01 00:00:00